Tuesday, August 26, 2008

nanotechnology in bio medical science

Disease and ill health are caused largely by damage at the molecular and cellular level. Today's surgical tools are, at this scale, large and crude. From the viewpoint of a cell, even a fine scalpel is a blunt instrument more suited to tear and injure than heal and cure. Modern surgery works only because cells have a remarkable ability to regroup, bury their dead and heal over the injury.

Nanotechnology, "the manufacturing technology of the 21st century," should let us economically build a broad range of complex molecular machines (including, not incidentally, molecular computers). It will let us build fleets of computer controlled molecular tools much smaller than a human cell and built with the accuracy and precision of drug molecules. Such tools will let medicine, for the first time, intervene in a sophisticated and controlled way at the cellular and molecular level. They could remove obstructions in the circulatory system, kill cancer cells, or take over the function of subcellular organelles. Just as today we have the artifical heart, so in the future we could have the artificial mitochondrion.

Equally dramatic, nanotechnology will give us new instruments to examine tissue in unprecedented detail. Sensors smaller than a cell would give us an inside and exquisitely precise look at ongoing function. Tissue that was either chemically fixed or flash frozen could be analyzed literally down to the molecular level, giving a completely detailed "snapshot" of cellular, subcellular and molecular activities.

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